EDUCATION

• 1995-1996: Postdoc, MIT, Cambridge, MA, USA, Department of Biology
• 1989-1990: Postdoc, Manchester University, UK, Department of Biology
• 1984-1989: PhD, MIT, Cambridge, MA, USA, Department of Biology - Middle East Technical University, Department of Biological Sciences
• 1981-1983: MSc., Middle East Technical University, Department of Biological Sciences
• 1975-1980: BSc., Hacettepe University, Department of Biology

AREA OF RESEARCH

Molecular Microbiology and Genetics

• Omic technologies and functional studies for Bacillus subtilis to analyse the role of the dipeptide antibiotic bacilysin as a small global regulator in cellular physiology
• Transcriptional regulation of cephamycin C biosynthetic gene cluster and pathway engineering to improve clavulanic acid and cephamycin C biosynthesis in Streptomyces clavuligerus
• Proteomics and immunoproteomics of Bordetella pertussis and development of novel subunit vaccines
• Development of OMV-based, re-designed and engineered vaccine platforms for pathogenic microbes.

SELECTED PUBLICATIONS

• Ünsaldı, E., Kurt-Kızıldoğan, A., Özcan, S., Becher, D., Voigt, B., Aktaş, C., and Özcengiz, G. (2021). Proteomic analysis of a hom-disrupted, cephamycin C overproducing Streptomyces clavuligerus. Protein and Peptide Letters, 28(2), 205–220.
• Ertekin, O., Kutnu, M., Taşkın, A.A., Demir, M., Yazgan Karataş, A. and Özcengiz, G. (2020). Analysis of a bac operon-silenced strain suggests pleiotropic effects of bacilysin in Bacillus subtilis. Journal of Microbiology. 58 (4): 297-313.
• Yılmaz, Ç. and Özcengiz G. (2017). Antibiotics: Pharmacokinetics, toxicity, resistance and multidrug efflux pumps. Biochemical Pharmacology. 133: 43-62.
• Ünsaldı, E., Kurt-Kızıldoğan, A., Voigt, B., Becher, D. and Özcengiz, G. (2017). Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus. Synthetic and Systems Biotechnology. 2: 39-48.
• Yılmaz, Ç., Apak, A., Özcengiz, E. and Özcengiz G. (2016). Immunogenicity and protective efficacy of recombinant iron superoxide dismutase protein from Bordetella pertussis in mice models. Microbiology and Immunology. 60: 717-724.
• Özcengiz, G. and Öğülür, İ. (2015). Biochemistry, genetics and regulation of bacilysin biosynthesis and its significance more than an antibiotic.New Biotechnology. 32: 612-619.